HOMOHARRINGTONINE DEMONSTRATES A CYTOTOXIC EFFECT AGAINST TRIPLE-NEGATIVE BREAST CANCER CELL LINES AND ACTS SYNERGISTICALLY WITH PACLITAXEL

Homoharringtonine demonstrates a cytotoxic effect against triple-negative breast cancer cell lines and acts synergistically with paclitaxel

Abstract The lack of targeted therapies for triple-negative breast cancer (TNBC) contributes to their high mortality rates and high risk of relapse compared to other subtypes of breast cancer.Most TNBCs (75%) have downregulated the expression of CREB3L1 (cAMP-responsive element binding protein 3 like Blackberry 1), a transcription factor and metast

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Double jeopardy: Successful management of a traumatic ascending aortic pseudoaneurysm with concurrent subdural hematoma

Cleaning Pads We present the case of a 59-year-old male who sustained an ascending aortic injury and a subdural hematoma after a head on collision.After undergoing emergent craniotomy for evacuation of the subdural hematoma, he was maintained with strict blood pressure control.Once able to be safely anticoagulated, he underwent replacement of the a

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Anthocyanins as functional food components

Among the natural pigments, anthocyanins are assumed to represent one of the most studied groups.Starting with the first studies on the physicochemical properties of anthocyanins carried out in the 17th century by British naturalist Robert Boyle, the science about these unique compounds has progressed substantially.To Butea Superba date, the struct

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